Into the labyrinth.
Seriously guys, the old layout was very much easier to use. With the current one there's a very poor distinction with what is and isn't clickable (it took me a while to find the [add comment] tag, especially with this enourmous font in such a narrow central column).
This one's just too confusing to the eyes, with the old FM you could pretty much skimread the columns without any effort at all - this one requires staring and concentration. Not good. The boxes around items are particularly conspicuous in their absence.
The best mail client (IMHO)
I've been using sylpheed since the early versions that used to explode from time to time ;-) It's now easily the best client I've used on a system (check out the multiple accounts support), and continues to mature. Nice to see it uses GTK themes properly too :-)